Glucophage XR
Metformin Hydrochloride · 500 mg · tablet
Glucophage XR details
- Active ingredient
- Metformin Hydrochloride
- Strength
- 500 mg
- Form
- tablet
- Drug class
- Biguanide antidiabetic (extended release)
- Manufacturer
- Merck Pakistan
- Registered in
- Pakistan
How does Glucophage XR work?
Lowers the amount of glucose the liver releases and helps muscle take up glucose more effectively. It does not force the pancreas to release insulin, which is why it rarely causes low blood sugar on its own.
How to take Glucophage XR
Take with or just after meals to reduce stomach upset. Doses are usually increased gradually. Extended-release forms are swallowed whole, never crushed.
Always follow the dose printed on your pack or given by your prescriber — it can differ from the general guidance above.
Common side effects
- • Nausea, diarrhoea or stomach cramps, especially in the first weeks
- • Metallic taste
- • Reduced appetite
Seek medical advice
- • Lactic acidosis (rare but serious) — deep rapid breathing, severe weakness, muscle pain, feeling very cold
- • Symptoms of vitamin B12 deficiency with long-term use — tingling, tiredness
Who should be careful with Glucophage XR?
- •Reduced kidney function — dose must be adjusted or the drug stopped
- •Stop temporarily before surgery or a scan using iodinated contrast dye
- •Dehydration, severe infection, or heavy alcohol use
Glucophage XR interactions
- •Iodinated contrast media used in CT scans
- •Alcohol — increases lactic acidosis risk
- •Other diabetes medicines — may increase the chance of low blood sugar
This is not a complete list. Tell your pharmacist about every medicine and supplement you take.
Other brands containing Metformin Hydrochloride
Frequently asked questions about Glucophage XR
What is Glucophage XR used for?
Glucophage XR contains Metformin Hydrochloride, a Biguanide antidiabetic (extended release). Check the package insert for the approved indications in Pakistan.
How does Glucophage XR work?
Lowers the amount of glucose the liver releases and helps muscle take up glucose more effectively. It does not force the pancreas to release insulin, which is why it rarely causes low blood sugar on its own.
How should I take Glucophage XR?
Take with or just after meals to reduce stomach upset. Doses are usually increased gradually. Extended-release forms are swallowed whole, never crushed. Always follow the dose on your pack or from your prescriber.
What are the side effects of Glucophage XR?
Common: Nausea, diarrhoea or stomach cramps, especially in the first weeks, Metallic taste, Reduced appetite. Seek medical advice for: Lactic acidosis (rare but serious) — deep rapid breathing, severe weakness, muscle pain, feeling very cold; Symptoms of vitamin B12 deficiency with long-term use — tingling, tiredness.
Is Glucophage XR available over the counter in Pakistan?
Glucophage XR is normally supplied on prescription in Pakistan. Speak to a doctor or pharmacist.
What are the alternatives to Glucophage XR?
Other brands containing the same active ingredient in Pakistan include Glucophage, Neodipar. They are not always interchangeable — check with a pharmacist.
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