Pakistan
Chemical structure of Glimepiride, the active ingredient in Amaryl
2D chemical structure of Glimepiride — via NIH PubChem

Amaryl

Glimepiride · 2 mg · tablet

Amaryl details

Active ingredient
Glimepiride
Strength
2 mg
Form
tablet
Drug class
Sulfonylurea antidiabetic
Manufacturer
Sanofi Pakistan
Registered in
Pakistan

How does Amaryl work?

Lowers the amount of glucose the liver releases and helps muscle take up glucose more effectively. It does not force the pancreas to release insulin, which is why it rarely causes low blood sugar on its own.

How to take Amaryl

Take with or just after meals to reduce stomach upset. Doses are usually increased gradually. Extended-release forms are swallowed whole, never crushed.

Always follow the dose printed on your pack or given by your prescriber — it can differ from the general guidance above.

Common side effects

  • Nausea, diarrhoea or stomach cramps, especially in the first weeks
  • Metallic taste
  • Reduced appetite

Seek medical advice

  • Lactic acidosis (rare but serious) — deep rapid breathing, severe weakness, muscle pain, feeling very cold
  • Symptoms of vitamin B12 deficiency with long-term use — tingling, tiredness

Who should be careful with Amaryl?

Amaryl interactions

This is not a complete list. Tell your pharmacist about every medicine and supplement you take.

Frequently asked questions about Amaryl

What is Amaryl used for?

Amaryl contains Glimepiride, a Sulfonylurea antidiabetic. Check the package insert for the approved indications in Pakistan.

How does Amaryl work?

Lowers the amount of glucose the liver releases and helps muscle take up glucose more effectively. It does not force the pancreas to release insulin, which is why it rarely causes low blood sugar on its own.

How should I take Amaryl?

Take with or just after meals to reduce stomach upset. Doses are usually increased gradually. Extended-release forms are swallowed whole, never crushed. Always follow the dose on your pack or from your prescriber.

What are the side effects of Amaryl?

Common: Nausea, diarrhoea or stomach cramps, especially in the first weeks, Metallic taste, Reduced appetite. Seek medical advice for: Lactic acidosis (rare but serious) — deep rapid breathing, severe weakness, muscle pain, feeling very cold; Symptoms of vitamin B12 deficiency with long-term use — tingling, tiredness.

Is Amaryl available over the counter in Pakistan?

Amaryl is normally supplied on prescription in Pakistan. Speak to a doctor or pharmacist.

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